In the September 1st issue of Lab on a Chip, Wang and colleagues report a proof-of-concept for an easily deployable, point-of-care diagnostic system for the detection of the ovarian cancer HE4 biomarker (reference). The team combined a simple microchip-based ELISA platform with the imaging capability of modern portable phones. Interestingly, the performances (sensitivity and specificity) of the portable phone camera appeared to be superior to a stand-alone CCD camera.
Although this work may seem anecdotal at first glance, it constitutes a valuable step towards increased diagnostic accessibility through the translation of a standard “high-tech” laboratory method to a “low-tech” broadly deployable platform.
Thierry
Sornasse for Integrated Biomarker Strategy
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